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Our vast experience means that we can offer you an extraordinarily talented group of laboratory experts, physicians, and genetic counselors, some of whom are former faculty members at leading universities or the National Institutes of Health (NIH).
PGT at Fairfax Diagnostics uses high resolution Next Generation Sequencing technology (NGS).
Results are ready in as little as 5 business days after sample is received by our lab and we will report PGT results no more than 7 days from sample receipt.
Our lab is headquartered conveniently in Fairfax, Virginia in the Washington, DC metropolitan region. Courier option available for shipping specimens within 25 mile radius of our laboratory.
Fairfax Diagnostics has over 38 years of experience in the field of assisted reproductive technology. Our expert team of molecular and clinical geneticists have been at the forefront of pioneering PGT test design, validation, and clinical application.
Fairfax Diagnostics was founded in 1984 in partnership with Genetics & IVF Institute as a complete embryo testing solution for couples pursuing IVF.
We maintain a zero-misdiagnosis rate in all PGT programs at Fairfax Diagnostics. Results are reviewed by a team molecular and clinical PhD/MD experts.
Looking for more information on PGT at Fairfax Diagnostics? Here are some frequently asked questions.
To appreciate how PGT can be helpful to couples it is important to understand chromosomes. Chromosomes are the physical structures made of DNA that contain the genes necessary for development. Chromosomes are located in the center of the cell, in the area called the nucleus. A normal human cell should contain exactly 46 chromosomes. There are 23 pairs of chromosomes. The first 22 pairs are identified by number and organized by size. The 23rd pair, the sex chromosomes, determines gender. Females have two of the same sex chromosome, called the X chromosome, while men have two different sex chromosomes, known as the X and Y chromosomes. A normal set of chromosomes is 46, XX for a female and 46, XY for a male. In a normal conception, both the egg and sperm cells should contribute exactly 23 individual chromosomes, one of each of the 22 numbered pairs (called autosomes) and one of the sex chromosome pair. When an egg with 23 chromosomes fuses with a sperm with 23 chromosomes, the correct chromosome number of 46 (23 pairs) is again present, and the fertilized embryo has the best possible chance of developing appropriately. When an egg or sperm cell divides improperly as it is developing, the mature egg or sperm may contain more or less than 23 chromosomes. If this egg or sperm is used for fertilization, the resulting embryo will not contain exactly 46 chromosomes, but more or less than 46, known as aneuploidy.
Preimplantation genetic testing (PGT) is performed by removing a few cells from the trophectoderm layer of a developing embryo at the blastocyst stage (day 5 or 6) during an in vitro fertilization cycle.
Yes. Substantial data indicates that PGT does not increase birth defects over that of the general population. Removal of a few cells from the outer layer (trophectoderm) does not alter the ability of that embryo to develop a normal pregnancy; in fact, biopsy avoids disrupting the embryo’s inner most cells that will form the fetus. In embryos undergoing PGT testing, many fewer pregnancies will end in miscarriages due to chromosomal disorders since abnormalities are identified prior to embryo transfer.
Embryos created using standard IVF protocols with intracytoplasmic sperm injection (ICSI) are grown in the laboratory for 5 to 6 days until they form an early embryo called a blastocyst. The embryo is subsequently biopsied to remove a few cells from the outer layer, also called a trophectoderm, which is destined to form the placenta.
After biopsy, embryos are frozen and stored while the cell’s genetic material is tested for abnormalities using PGT. After PGT analysis, results are evaluated by the medical and genetics teams, then a Fairfax Diagnostics genetic counselor will discuss results with the patient/couple and a frozen embryo transfer (FET) cycle is planned for the healthy embryo(s).