The authors of this review published in the International Journal of Molecular Sciences provide a comprehensive and detailed discussion of the PGT process covering the key steps from embryo biopsy to molecular methods used for embryo analysis to maternal and neonatal outcomes. The level of discussion is geared to practitioners of reproductive medicine but can be of value to the general public interested in learning some of the indications for infertility and approaches used to address specific treatment options based on patient medical history. The main focus is PGT-A, but details of the use of PGT-M for monogenic disorders are presented by the author as well. Included is a discussion of the underlying aspects of a phenomenon known as mosaicism and how it can be managed with respect to choosing the appropriate embryos for uterine transfer.
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